Vantolin Introduction
Vantolin, Generic name is albuterol or salbutamol and it is
a short-acting β2-adrenergic receptor agonist used for the
relief of bronchospasm in conditions such as asthma and COPD.
The inhaled route for direct effect on bronchial smooth
muscle usually gives Vantolin. This is usually achieved
through a nebuliser, metered dose inhaler or other
proprietary delivery devices (e.g. Rotahaler or Autohaler).
In these forms of delivery, the effect of ventolin can take
place within 5 to 20 minutes of dosing. Ventolin can also be
given orally or intravenously. However, some asthmatics may
not respond to these medications, as they will not have the
required DNA base sequence in a specific genetic material.
Ventolin is specifically indicated in the following
conditions: acute asthma, symptom relief during maintenance
therapy of asthma and other conditions with reversible
airways obstruction (including COPD), hyperkalemia,
protection against exercise-induced asthma, hyperkalemia,
especially in patients with renal failure can be aerosolized
for patients with Cystic Fibrosis, along with pulmozyme and
ipratropium bromide. As a β2-agonist,
Ventolin also finds
use in obstetrics. Intravenous Vantolin can be used as a
tocolytic to relax the uterine smooth muscle to delay
premature labour. Whilst preferred over agents such as
ritodrine and atosiban, its role has been largely replaced
by the calcium-channel blocker nifedipine, which is more
effective, better tolerated and orally administered.
While Vintolin is well tolerated, particularly when compared
with other therapies such as theophylline, like all
medications there exists the potential for adverse drug
reactions to occur - especially when in heavy doses, or when
taken orally or intravenously. Common adverse effects
include: tremor, headache and palpitations. Infrequent
adverse effects include: tachycardia, agitation muscle
cramps, agitation, hypokalemia, hyperactivity in children,
and insomnia.
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